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Genetic variation at the SLCO1B1 gene locus and low density lipoprotein cholesterol lowering response to pravastatin in the elderly

✍ Scribed by Hironobu Akao; Eliana Polisecki; Kouji Kajinami; Stella Trompet; Michele Robertson; Ian Ford; J. Wouter Jukema; Anton J.M. de Craen; Rudi G.J. Westendorp; James Shepherd; Christopher Packard; Brendan M. Buckley; Ernst J. Schaefer


Book ID
118423859
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
207 KB
Volume
220
Category
Article
ISSN
0021-9150

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## Abstract Circulating levels of low‐density lipoprotein (LDL) vary considerably within and between populations, paralleled by differing coronary heart disease (CHD) mortality rates. We have previously shown that variation in the apolipoprotein (apo) B gene as associated with certain restriction f