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Genetic variants of CYP19 (aromatase) and breast cancer risk

✍ Scribed by Kristensen, Vessela Nedelcheva; Harada, Nobuhiro; Yoshimura, Noriko; Haraldsen, Ellen; Lønning, P E; Erikstein, Bjørn; Kåresen, Rolf; Kristensen, Tom; Børresen-Dale, Anne-Lise

Book ID
110062771
Publisher
Nature Publishing Group
Year
2000
Tongue
English
Weight
159 KB
Volume
19
Category
Article
ISSN
0950-9232

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✍ Randi A. Paynter; Susan E. Hankinson; Graham A. Colditz; Peter Kraft; David J. H 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 French ⚖ 146 KB 👁 1 views

## Abstract Endogenous estrogen exposure is an important determinant of endometrial cancer risk. Aromatase, encoded by __CYP19,__ catalyzes the aromatization of androstenedione and testosterone to estrone and estradiol, respectively. Several common genetic polymorphisms in __CYP19__ have been ident