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CYP17genetic polymorphism, breast cancer, and breast cancer risk factors

✍ Scribed by Christine B Ambrosone, Kirsten B Moysich, Helena Furberg…

Book ID
120701066
Publisher
BioMed Central
Year
2003
Tongue
English
Weight
72 KB
Volume
5
Category
Article
ISSN
1465-5411

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Long-term exposure to oestrogens is a well-recognised risk factor for breast cancer, whereas little is known about the influence of polymorphisms of genes involved in oestrogen biosynthesis and metabolism. A candidate, containing a single bp polymorphism, T8C, (designated, A2 allele), might be the C