Genetic variants of C1orf10 and risk of esophageal squamous cell carcinoma in a Chinese population
โ Scribed by Wei Zhang; Xiabin Chen; Aiping Luo; Dongxin Lin; Wen Tan; Zhihua Liu
- Book ID
- 108586457
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 619 KB
- Volume
- 100
- Category
- Article
- ISSN
- 1347-9032
No coin nor oath required. For personal study only.
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## Abstract Because previous studies have shown that loss of heterozygosity (LOH) is common on chromosome arm 9p in esophageal squamous cell carcinoma (ESCC) and that genetic alterations in __CDKN2A__ and __CDKN2B__ on 9p are also common, we sought to determine whether LOH and these genetic alterat
## Abstract Two nonโsynonymous polymorphisms Arg194Trp and Arg399Gln in the DNAโbase excision repair gene Xโray repair crossโcomplementing group 1 (__XRCC1__) have been implicated in risk for esophageal cancer. However, the results from different studies remain controversial. The present metaโanaly
## Abstract Esophageal squamous cell carcinoma (ESCC), which is prevalent in China, is believed to be induced by environmental carcinogens. Accumulating evidence has shown that individual variation in DNA repair capacity resulting from genetic polymorphism influences risk of environmental carcinoge