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Genetic variant in CASP3 affects promoter activity and risk of esophageal squamous cell carcinoma

✍ Scribed by Zhi Zhang; Xinfeng Yu; Yongli Guo; Wenguang Song; Dianke Yu; Xuemei Zhang


Book ID
114703149
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
178 KB
Volume
103
Category
Article
ISSN
1347-9032

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## Abstract Functional SNPs in the __COX‐2__ promoter region have been associated with susceptibility to esophageal squamous‐cell carcinoma (ESCC). In this study, we investigated SNPs in the __COX‐2__ coding region and their impact on risk of ESCC. The coding region of __COX‐2__ in DNAs from 30 Han