𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Genetic validation of β-secretase as a drug target for Alzheimer's Disease

✍ Scribed by MLE MacDonald


Book ID
110887900
Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
713 KB
Volume
65
Category
Article
ISSN
0009-9163

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


β-secretase as a target for the treatmen
✍ Martin Citron 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 490 KB 👁 1 views

## Abstract Finding inhibitors of the first step of the amyloid cascade, Aβ~42~ generation, is a major goal of Alzheimer's disease drug development. Two target protease activities, β‐and γ‐secretase, were detected more than 10 years ago but progress in this area has been slow because the enzymes we