๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Genetic testing in endocrinology: lessons learned from experience with multiple endocrine neoplasia type 2 (MEN2)

โœ Scribed by Camilo Jimenez; Robert F. Gagel


Book ID
116511995
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
275 KB
Volume
14
Category
Article
ISSN
1096-6374

No coin nor oath required. For personal study only.


๐Ÿ“œ SIMILAR VOLUMES


Presymptomatic genetic screening in fami
โœ A. Frilling; W. Hรถppner; C. Eng; L. Mulligan; F. Raue; C. E. Broelsch ๐Ÿ“‚ Article ๐Ÿ“… 1995 ๐Ÿ› Springer ๐ŸŒ English โš– 474 KB

Medullary thyroid carcinoma occurs sporadically or as a part of the inherited cancer syndrome multiple endocrine neoplasia (MEN) type 2. The MEN 2 gene has been identified as the RET proto-oncogene on chromosome 10. In MEN 2A, RET mutations are detectable in one of five cysteine codons within exons

Genetic analysis of RET, GFRฮฑ1 and GDNF
โœ Laura Gil; Marta Azaรฑedo; Marina Pollรกn; Eva Cristobal; Begoรฑa Arribas; Luis Gar ๐Ÿ“‚ Article ๐Ÿ“… 2002 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 112 KB ๐Ÿ‘ 1 views

## Abstract Multiple endocrine neoplasia type 2A (MEN 2A) is associated with specific germline missense mutations in the __RET__ protoโ€oncogene. This locus encodes a receptor tyrosine kinase whose activation requires the formation of a multimeric receptor complex including GDNF as a ligand and GFRฮฑ