✦ LIBER ✦

Genetic susceptibility to type 1 diabetes

✍ Scribed by Lisa M Maier; Linda S Wicker

Publisher: Elsevier Science
Year: 2005
Tongue: English
Weight: 159 KB
Volume: 17
Category: Article
ISSN: 0952-7915
DOI: 10.1016/j.coi.2005.09.013

No coin nor oath required. For personal study only.

✦ Synopsis

The recent discovery of PTPN22 as a novel susceptibility gene in human type 1 diabetes and continued progress in defining genes in animal models of the disease mark a fruitful period in the field of type 1 diabetes genetics. In addition, the similarities of the genetic and functional aspects across species have been substantiated. Future genomewide association studies will reveal more loci, each providing a piece to the genetic puzzle of autoimmune disease.

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