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Genetic polymorphisms in phase I and phase II enzymes and breast cancer risk associated with menopausal hormone therapy in postmenopausal women

✍ Scribed by The MARIE-GENICA Consortium on Genetic Susceptibility for Menopausal Hormone Therapy Related Breast Cancer Risk

Publisher
Springer US
Year
2009
Tongue
English
Weight
203 KB
Volume
119
Category
Article
ISSN
0167-6806

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## Abstract Menopausal hormone therapy (HT) is associated with increased breast cancer risk among postmenopausal women. Nuclear receptors are involved in steroid hormone‐ and xenobiotic‐mediated signal transduction playing a crucial role in regulating gene expression. Therefore, variations within t