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Genetic polymorphisms in metabolism of 2-amino-1-methyl-6-phenylimidazo[4,5-b] pyridine

✍ Scribed by Dojung Kim; Young-Joo Lee; Heui-Young Ryu; Jin-Hee Lee; Hyun-Kyung Kim; Eunhee Kim; Jae-Dong Moon; Dong Deuk Chang; Hae-Seong Yoon


Book ID
112117716
Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
624 KB
Volume
33
Category
Article
ISSN
0260-437X

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## Abstract 2‐amino‐1‐methyl‐6‐phenylimidazo[4,5‐__b__]pyridine (PhIP) is the most abundant heterocyclic amine derived from food, possibly involved in human carcinogenesis. We evaluated the formation of PhIP‐DNA adducts in lymphocytes from 76 incident colorectal cancer patients likely to be exposed