2-Amino-1-methyl-6-phenylimidazo(4,5-b)pyridine (PhIP), a compound found in cooked meat, is a mammary gland carcinogen in female Sprague-Dawley rats. PhIP-induced rat mammary gland carcinomas were examined for mutations in several genes (exons) known to regulate cell growth and apoptosis, including
DNA Modification by 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in Rats
β Scribed by Takayama, Kyoko ;Yamashita, Katsumi ;Wakabayashi, Keiji ;Sugimura, Takashi ;Nagao, Minako
- Book ID
- 108578791
- Publisher
- Wiley (Blackwell Publishing)
- Year
- 1989
- Tongue
- English
- Weight
- 347 KB
- Volume
- 80
- Category
- Article
- ISSN
- 0910-5050
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