Genetic polymorphism of murine tissue plasminogen activator associated with antiphospholipid syndrome
β Scribed by Shirai, J; Ida, A; Jiang, Y; Sanokawa-Akakura, R; Miura, Y; Yan, K; Hamano, Y; Hirose, S; Shirai, T
- Book ID
- 110037201
- Publisher
- Nature Publishing Group
- Year
- 1999
- Tongue
- English
- Weight
- 235 KB
- Volume
- 1
- Category
- Article
- ISSN
- 1466-4879
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π SIMILAR VOLUMES
## Objective: To investigate the relationship between the 4g/5g polymorphism of the type 1 plasminogen activator inhibitor (pai-1) gene and thrombotic manifestations in patients with antiphospholipid syndrome (aps). ## Methods: We studied a total of 247 patients included in the following 4 groups
A new case of congenital hypodysfibrinogenemia associated with a thrombotic tendency (thrombosis of the peroneal artery, the pulmonary artery and the deep veins of the lower extremities), is reported. Clotting time using Reptilase was significantly prolonged. The low levels of plasma fibrinogen were