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Genetic polymorphism of human phosphoglycolate phosphatase (PGP)

✍ Scribed by R. F. BARKER; D. A. HOPKINSON

Book ID
115248635
Publisher
John Wiley and Sons
Year
1978
Tongue
English
Weight
627 KB
Volume
42
Category
Article
ISSN
0003-4800

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PGP (phosphoglycolate phosphatase, E.C. 3.1.3.18) phenotypes were determined by starch gel electrophoresis in 272 mother-child pairs from S. W. Germany. The results confirm and formal hypothesis of three alleles, PGP1, PGP2 and PGP3 at an autosomal locus PGP.

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One hundred and sixty-seven blood donors, 26 families with 72 offspring and 12 motherchild couples were studied for the phosphoglycolate phosphatase polymorphism. In hemolysates, the isozymes are stable for at least five weeks. The distribution of observed phenotypes in the population study did not