Biochemical characterization of the genetic variants of human phosphoglycolate phosphatase (PGP)
β Scribed by V. S. TURNER; D. A. HOPKINSON
- Book ID
- 115248886
- Publisher
- John Wiley and Sons
- Year
- 1981
- Tongue
- English
- Weight
- 392 KB
- Volume
- 45
- Category
- Article
- ISSN
- 0003-4800
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PGP (phosphoglycolate phosphatase, E.C. 3.1.3.18) phenotypes were determined by starch gel electrophoresis in 272 mother-child pairs from S. W. Germany. The results confirm and formal hypothesis of three alleles, PGP1, PGP2 and PGP3 at an autosomal locus PGP.
One hundred and sixty-seven blood donors, 26 families with 72 offspring and 12 motherchild couples were studied for the phosphoglycolate phosphatase polymorphism. In hemolysates, the isozymes are stable for at least five weeks. The distribution of observed phenotypes in the population study did not