An assessment has been made of the polymorphism of human complement component C4 by comparing derived amino acid sequences of cDNA and genomic DNA with limited amino acid sequences. In all, one complete and six partial sequences have been obtained from material from three individuals and include two
Genetic polymorphism of human complement C4 and detection of heterozygotes
β Scribed by Awdeh, Z. L.; Raum, D.; Alper, C. A.
- Book ID
- 109716655
- Publisher
- Nature Publishing Group
- Year
- 1979
- Tongue
- English
- Weight
- 351 KB
- Volume
- 282
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/282205a0
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## Abstract Human complement factorβ H (factorβ H) is polymorphic, with five previously reported FH alleles and three previously reported HF alleles (HF\*A, HF\*B, and HF\*Q0). The relationship between the FH and HF alleles is not clear, and the genetic basis of factorβ H phenotypes has not yet been i