Proteins were separated by prolonged isoelectric focusing in polyacrylamide gels, whereupon C2 bands were detected by a specific hemolytic assay. This was performed by treating the gel with iodine to increase C2 activity, and then developing C2 bands with an agarose gel overlay containing sensitized
✦ LIBER ✦
Genetic polymorphism of the human complement component C′3 among North Germans
✍ Scribed by Swadesh Seth; Helmut Berndt
- Publisher
- Springer
- Year
- 1974
- Tongue
- English
- Weight
- 153 KB
- Volume
- 21
- Category
- Article
- ISSN
- 0340-6717
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A C7 cDNA probe detecting a TaqI restriction fragment length polymorphism has been used to examine the segregation of the "silent allele" (C7\*Q0) in two familial deficiencies. Carrier diagnosis in healthy children is possible when both parents are heterozygotes. Only one of these two families was i