## BACKGROUND. Multiple intraesophageal primary cancer and upper aerodigestive tract (UADT) cancer associated uith esophageal cancer are common diseases, especially in heavy drinkers. Thev are often explained by the concept of field cancerization, which suggests a similar etiology. However, little
Genetic Polymorphism of Aldehyde Dehydrogenase 2 in Patients With Upper Aerodigestive Tract Cancer
โ Scribed by Hiroki Tanabe; Motoyuki Ohhira; Tikara Ohtsubo; Jiro Watari; Kinichi Yokota; Yutaka Kohgo
- Book ID
- 109121472
- Publisher
- John Wiley and Sons
- Year
- 1999
- Tongue
- English
- Weight
- 459 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0145-6008
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In this study, 1,000 Japanese male alcoholics were consecutively screened by upper gastrointestinal endoscopy with esophageal iodine staining. Associations among cancer-detection rates, drinking and smoking habits, and aldehyde dehydrogenase-2 (ALDH2) genotypes were evaluated. A total of 53 patients
Some studies have shown that human papillomavirus (HPV) infection may play not only an etiologic role in anogenital cancers but also a role in the clinical outcome. The objective of the current study was to determine whether detection of HPV DNA in primary squamous cell carcinomas of the upper aerod