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Multiple primary esophageal and concurrent upper aerodigestive tract cancer and the aldehyde dehydrogenase-2 genotype of Japanese alcoholics

✍ Scribed by Akira Yokoyama; Taro Muramatsu; Tai Ohmori; Hiroyasu Makuuchi; Susumu Higuchi; Sachio Matsushita; Keiichi Yoshino; Katsuya Maruyama; Masayuki Nakano; Hiromasa Ishii

Publisher: John Wiley and Sons
Year: 1996
Tongue: English
Weight: 536 KB
Volume: 77
Category: Article
ISSN: 0008-543X
DOI: 10.1002/(sici)1097-0142(19960515)77:10<1986::aid-cncr4>3.0.co;2-f

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✦ Synopsis

BACKGROUND.

Multiple intraesophageal primary cancer and upper aerodigestive tract (UADT) cancer associated uith esophageal cancer are common diseases, especially in heavy drinkers. Thev are often explained by the concept of field cancerization, which suggests a similar etiology. However, little is known about the nature of the hypothesized etiology.

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