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Genetic polymorphism and activities of human lung alcohol and aldehyde dehydrogenases: Implications for ethanol metabolism and cytotoxicity

✍ Scribed by Shih-Jiun Yin,Chin-Shya Liao,Chun-Mei Chen,Fa-Ti Fan…

Book ID
118776562
Publisher
Springer
Year
1992
Tongue
English
Weight
695 KB
Volume
30
Category
Article
ISSN
0006-2928

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Two types of factors can theoretically modulate alcohol metabolism toward increased acetaldehyde production. These factors are the following: (a) individual, genetically determined isoenzymes with distinct catalytic properties, and (b) modifications of enzyme activity induced by alcohol itself or li