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Genetic Mutations Identified for Hereditary Diffuse Gastric Cancer

✍ Scribed by Les Lang

Book ID
119759936
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
92 KB
Volume
133
Category
Article
ISSN
0016-5085

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## Abstract ## BACKGROUND. A subset of patients with diffuse gastric cancer harbor deleterious cancer‐causing germline mutations in the type 1 E‐cadherin (epithelial) gene (__CDH1__), which predisposes to the autosomal dominantly inherited hereditary diffuse gastric cancer (HDGC) syndrome. These m