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Genetic Modulation of PPARγ Phosphorylation Regulates Insulin Sensitivity

✍ Scribed by Shamina M. Rangwala; Ben Rhoades; Jennifer S. Shapiro; A.Sophie Rich; Jason K. Kim; Gerald I. Shulman; Klaus H. Kaestner; Mitchell A. Lazar

Book ID
117795438
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
295 KB
Volume
5
Category
Article
ISSN
1534-5807

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## Abstract The anti‐diabetic thiazolidinediones (TZDs) are a class of compounds with insulin‐sensitizing activity that were originally discovered using in vivo pharmacological screens. In subsequent binding studies, TZDs were demonstrated to enhance insulin action by activating peroxisome prolifer