Advances in lentiviral vector design for
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Aaron C Logan; Carolyn Lutzko; Donald B Kohn
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Article
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2002
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Elsevier Science
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English
⚖ 84 KB
Lentiviral vectors are more efficient at transducing quiescent hematopoietic stem cells than murine retroviral vectors. This characteristic is due to multiple karyophilic components of the lentiviral vector pre-integration complex. Lentiviral vectors are also able to carry more complex payloads than