Genetic linkage between the loci for myotonic dystrophy and peptidase D
β Scribed by T. O'BRIEN; S. BALL; M. SARFARAZI; P. S. HARPER; E. B. ROBSON
- Book ID
- 115249074
- Publisher
- John Wiley and Sons
- Year
- 1983
- Tongue
- English
- Weight
- 234 KB
- Volume
- 47
- Category
- Article
- ISSN
- 0003-4800
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π SIMILAR VOLUMES
A set of nine polymorphic loci defined by DNA probes was studied for linkage with the disease locus in ten families with a history of Duchenne muscular dystrophy (DMD), and three families with a history of Becker muscular dystrophy (BMD). The results confirm DMD and BMD linkage to all marker loci an
We used the following polymorphic markers: APOC2 (BanI, BglI, TaqI), CKMM (NcoI, TaqI), and D19S63 (PstI) to haplotype 33 Spanish myotonic dystrophy (DM) families. We analysed the allele and haplotype frequencies of our sample, and the possible association of alleles or haplotypes with the disease.