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Genetic linkage analysis of nerve growth factor (beta) in familial alzheimer's disease

✍ Scribed by Dr. Marchk J. Alberts; Margaret A. Pericak-Vance; Vernice Royal; Jackie Bebout; Peter Gaskell; John Thomas; Wu-Yen Hung; Chris Clark; Nancy Earl; Allen D. Roses


Publisher
John Wiley and Sons
Year
1991
Tongue
English
Weight
366 KB
Volume
30
Category
Article
ISSN
0364-5134

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## Abstract We performed linkage analysis for age at onset (AAO) in the total Alzheimer's disease (AD) NIMH sample (N = 437 families). Families were subset as late‐onset (320 families, AAO β‰₯65) and early/mixed (117 families, at least 1 member with 50< AAO <65). Treating AAO as a censored trait, we