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Genetic instability in Thorotrast induced liver cancers

โœ Scribed by Duo Liu; Hirohito Momoi; Li Li; Yuichi Ishikawa; Manabu Fukumoto


Book ID
117549984
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
59 KB
Volume
1236
Category
Article
ISSN
0531-5131

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Thorotrast, a colloidal suspension of radioactive (232)ThO(2) that emits alpha particles, was used as a radiographic contrast during World War II. It is known to induce liver cancers, most frequently ICC, decades after injection. Since radiation induces genomic instability, we analyzed MSI in Thorot

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