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Genetic instability in colorectal cancer

โœ Scribed by THOMAS, H J W

Book ID
115497303
Publisher
BMJ Publishing Group
Year
1998
Tongue
English
Weight
159 KB
Volume
43
Category
Article
ISSN
0017-5749

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Microsatellite instability in colorectal
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Hereditary non-polyposis colorectal cancer (HNPCC) is a dominantly inherited syndrome linked to DNA-mismatch-repair (MMR) gene defects, which also account for microsatellite instability (MSI) in tumour tissues. Diagnosis is based mainly on family history, according to widely accepted criteria (Amste