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Genetic heterogeneity in susceptibility to autoimmune hepatitis types 1 and 2

✍ Scribed by Paulo L. Bittencourt; Anna C. Goldberg; Eduardo L.R. Cançado; Gilda Porta; Flair J. Carrilho; Alberto Q. Farias; Selma A. Palacios; Josely M. Chiarella; Clarice P. Abrantes-Lemos; Vera L. Baggio; Antonio A. Laudanna; Jorge Kalil

Book ID
119396416
Publisher
Nature Publishing Group
Year
1999
Tongue
English
Weight
71 KB
Volume
94
Category
Article
ISSN
0002-9270

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HLA-C genes and susceptibility to type 1
HLA-C genes and susceptibility to type 1 autoimmune hepatitis
✍ M D Strettell; L J Thomson; P T Donaldson; M Bunce; C M O'Neill; R Williams 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 189 KB

Susceptibility to autoimmune hepatitis (AIH) is associated with the HLA A1-B8-DR3 haplotype, DR4 antigen, and, more specifically, the HLA DRB3\*0101, DRB1\*0301, and DRB1\*0401 alleles. Few investigators, however, have examined the HLA C locus in AIH, which warrants detailed study in view of its rec