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Genetic evidence for functional role of ryanodine receptor 1 in pulmonary artery smooth muscle cells

✍ Scribed by Xiao-Qiang Li; Yun-Min Zheng; Rakesh Rathore; Jianjie Ma; Hiroshi Takeshima; Yong-Xiao Wang


Book ID
106110222
Publisher
Springer
Year
2008
Tongue
English
Weight
486 KB
Volume
457
Category
Article
ISSN
0031-6768

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## Abstract Sphingosine‐1‐phosphate (S1P), acting through five closely related G‐protein coupled receptors termed S1P~1–5~, has recently emerged as a possible regulator of smooth muscle cell (SMC) physiology with the potential to induce contraction, proliferation and stress fiber formation. In the