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Genetic epidemiology of complex phenotypes

โœ Scribed by N. E. Morton; D. C. Shields; A. Collins

Book ID
115249468
Publisher
John Wiley and Sons
Year
1991
Tongue
English
Weight
989 KB
Volume
55
Category
Article
ISSN
0003-4800

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Epidemiology of the delta globin alleles
Epidemiology of the delta globin alleles in southern Italy shows complex molecular, genetic, and phenotypic features
โœ Maria De Angioletti; Giuseppina Lacerra; Carlo Gaudiano; Gabriella Mastrolonardo ๐Ÿ“‚ Article ๐Ÿ“… 2002 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 302 KB

We characterized mutations and haplotypes of the delta-globin gene (HBD, MIM# 142000) in two regions of southern Italy. Mutations were discovered by screening for individuals with Hb A2<2%. In Basilicata, about 10,000 students were screened and 53 carriers in 43 unrelated families were diagnosed; in