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Genetic effect of single-nucleotide polymorphisms in the PPARGC1B gene on airway hyperreactivity in asthmatic patients

✍ Scribed by S.-H. Lee; A.-S. Jang; S. Woo Park; J. -S. Park; Y. K. Kim; S.-T. Uh; Y. H. Kim; I. Y. Chung; B.–L. Park; H. D. Shin; C.-S. Park


Book ID
108689007
Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
504 KB
Volume
41
Category
Article
ISSN
0954-7894

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## Abstract The adenosine A~2B~ receptor is found on human lung mast cells and is believed to mediate the bronchoconstriction in response to adenosine characteristic of asthmatics. As such it represents an attractive therapeutic target for asthma and allergic rhinitis. As genetic variability in dru