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Genetic dissection of the methylcytosine-specific restriction system mcrB of Escherichia coli K-12

โœ Scribed by Dila, Deborah; Raleigh, Elisabeth A.


Book ID
123479407
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
173 KB
Volume
74
Category
Article
ISSN
0378-1119

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The McrB restriction system in Escherichia coli K12 causes sequence-specific recognition and inactivation of DNA containing 5-methylcytosine residues. We have previously located the mcrB gene near hsdS at 99 min on the E. coli chromosome and demonstrated that it encodes a 51 kDa polypeptide required