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Genetic dissection of phosphate- and vitamin D-mediated regulation of circulating Fgf23 concentrations

✍ Scribed by Xijie Yu; Yves Sabbagh; Siobhan I. Davis; Marie B. Demay; Kenneth E. White

Book ID
116319156
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
249 KB
Volume
36
Category
Article
ISSN
8756-3282

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## Abstract The functional interaction between fibroblast growth factor 23 (FGF‐23) and Klotho in the control of vitamin D and phosphate homeostasis is manifested by the largely overlapping phenotypes of __Fgf23‐__ and __Klotho‐__deficient mouse models. However, to date, targeted inactivation of FG