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FGF-23 Is a Potent Regulator of Vitamin D Metabolism and Phosphate Homeostasis

✍ Scribed by Takashi Shimada; Hisashi Hasegawa; Yuji Yamazaki; Takanori Muto; Rieko Hino; Yasuhiro Takeuchi; Toshiro Fujita; Kazuhiko Nakahara; Seiji Fukumoto; Takeyoshi Yamashita

Book ID
111485026
Publisher
American Society for Bone and Mineral Research
Year
2003
Tongue
English
Weight
291 KB
Volume
19
Category
Article
ISSN
0884-0431

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## Abstract The functional interaction between fibroblast growth factor 23 (FGF‐23) and Klotho in the control of vitamin D and phosphate homeostasis is manifested by the largely overlapping phenotypes of __Fgf23‐__ and __Klotho‐__deficient mouse models. However, to date, targeted inactivation of FG