✦ LIBER ✦

Genetic dissection of Ca2+-dependent ion channel function in Paramecium

✍ Scribed by Robin R. Preston

Publisher: John Wiley and Sons
Year: 1990
Tongue: English
Weight: 1001 KB
Volume: 12
Category: Article
ISSN: 0265-9247
DOI: 10.1002/bies.950120605

No coin nor oath required. For personal study only.

✦ Synopsis

possible associations with other cytoplasmic or intramembranous proteins. If we are to understand fully all of the actions and interactions of ion channels, ideally, we must be able to selectively disrupt the functions of individual ion channel subunits and of any elements involved in regulating the activity of these ion channels. The ciliated protozoan Paramecium provides just such an opportunity.

📜 SIMILAR VOLUMES

Induction of Na+ channel voltage sensiti

Induction of Na+ channel voltage sensitivity in Xenopus oocytes depends on Ca2+ mobilization

✍ Gilles Charpentier; Raymond T. Kado 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 240 KB

An unusual inward current which is slowly elicited in the Xenopus oocyte membrane during sustained depolarization is reportedly carried by Na ϩ . It is thought that Na ϩ selective channels are in some way induced to become voltagesensitive by the depolarization. Earlier studies report that the induc

Temperature dependence of herium-ion cha

Temperature dependence of herium-ion channeling in NiCr2O4 single crystals

✍ T. Haga; K. Shimizu; Y. Abe; Y. Kino 📂 Article 📅 1981 🏛 Elsevier Science 🌐 English ⚖ 201 KB

Na+ and Ca2+ channel expression in cultu

Na+ and Ca2+ channel expression in cultured newt retinal pigment epithelial cells: Comparison with neuronal types of ion channels

✍ Sakai, Hideto ;Saito, Takehiko 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 345 KB 👁 3 views

We cultured retinal pigment epitheinactivation curve tended to be less in cultured RPE lial (RPE) cells dissociated from adult newt eye and cells than in neurons, and the half-inactivation voltage analyzed their voltage-gated ion channels during culwas about 054 mV for the RPE cells and 045 mV for t

Existence, properties, and functional ex

Existence, properties, and functional expression of “Maxi-K”-type, Ca2+-activated K+ channels in short-term cultured hepatocytes

✍ Darlene C. Pon; Ceredwyn E. Hill 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 218 KB 👁 1 views

A large-conductance, Ca 2/ -activated K / channel was identified and characterized in embryonic chick hepatocytes using the patch-electrode voltage-clamp technique. The channel conductance was 213 pS in excised patches bathed in symmetrical 145 mM KCl and 1 mM Ca 2/ . Current-voltage relationships w

Functional expression of constitutive ni

Functional expression of constitutive nitric oxide synthases regulated by voltage-gated Na+ and Ca2+ channels in cultured human astrocytes

✍ Michiko Oka; Miyuki Wada; Akira Yamamoto; Yoshinori Itoh; Takuya Fujita 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 437 KB

## Abstract We report the functional characterization of constitutive nitric oxide synthase(s) (NOS) such as neuronal and endothelial NOS in cultured human astrocytes. Exposure of cultured human astrocytes to 1 μM veratridine or 50 mM KCl produced a pronounced increase in a calmodulin‐dependent NOS

A Ca2+ - and pH-Dependent K+ Channel of

A Ca2+ - and pH-Dependent K+ Channel of rat C6 glioma cells and its possible role in acidosis-induced cell swelling

✍ Dr. Michael Strupp; Frank Staub; Peter Grafe 📂 Article 📅 1993 🏛 John Wiley and Sons 🌐 English ⚖ 932 KB

The aim of the present study was to explore whether a change in membrane K+ conductance contributes to acidosis-induced swelling of cultured rat C6 glioma cells. Electrophysiological studies were performed using whole-cell and single-channel recordings in combination with cell volume measurements in