Genetic Differences Between BRCA-Associated and Sporadic Ovarian Cancer DNA
β Scribed by C.S. Walsh; S. Ogawa; D. Scoles; J. Pavelka; C. Miller; N. Kawamata; S. Narod; H.P. Koeffler; B.Y. Karlan
- Book ID
- 113961286
- Publisher
- Elsevier Science
- Year
- 2007
- Tongue
- English
- Weight
- 62 KB
- Volume
- 107
- Category
- Article
- ISSN
- 0090-8258
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
The genetic changes underlying the development and progression of male breast cancer are poorly understood. Germline BRCA2 mutations account for a significant part of male breast cancer, but the majority of patients lack a known inherited predisposition. We recently demonstrated that the progression
## Abstract Index cases from a clinically relevant cohort of 102 Spanish families with at least 3 cases of breast and/or ovarian cancer (at least 1 case diagnosed before age 50) in the same lineage were screened for germline mutations in the entire coding sequence and intron boundaries of the breas
## Abstract This study compares __Br__east __Ca__ncer 1 (__BRCA1__) and excision repair cross complementation group 1 (__ERCC1__) expression as predictive markers and evaluates the __in vitro__ enhancement of platinum sensitivity using targeted agents in sporadic ovarian cancer (OC). A retrospectiv