The preimplantation period of mammalian development is characterized by cleavage of a one-cell embryo to a blastocyst stage embryo. During preimplantation development, 15%-50% of the embryos die as a result of factors that are largely unknown. Two parameters of preimplantation development, a fast ra
Genetic diagnosis of the preimplantation embryo
β Scribed by Buster, John E. ;Carson, Sandra A.
- Publisher
- John Wiley and Sons
- Year
- 1989
- Tongue
- English
- Weight
- 635 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0148-7299
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Preimplantation genetic diagnosis (PGD) can be offered as an alternative to prenatal diagnosis (PND) to couples at risk of having a child with a genetic disease. The affected embryos are detected before implantation by fluorescent in situ hybridisation (FISH) for sexing (X-linked diseases) and chrom