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Genetic counseling and genetic heterogeneity in the thalassemias

✍ Scribed by E. Paglietti; R. Galanello; M. Addis; A. Cao


Book ID
115089269
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
394 KB
Volume
28
Category
Article
ISSN
0009-9163

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## Abstract Thalassemias are a group of genetic hemolytic disorders with varying phenotypes. In this study, the frequency of Ξ± globin gene deletions was studied in the β‐thalassemia trait, the mildest form of the disorder. Eleven out of 33 (33%) individuals were positive for Ξ±^βˆ’3.7 kb^ deletions. N