Genetic Control of Mitochondrial Enzymes in Human–Mouse Somatic Cell Hybrids
✍ Scribed by VAN HEYNINGEN, VERONICA; CRAIG, I.; BODMER, W.
- Book ID
- 109685668
- Publisher
- Nature Publishing Group
- Year
- 1973
- Tongue
- English
- Weight
- 496 KB
- Volume
- 242
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/242509a0
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
The maintenance of mtDNA has been examined in human intraspecific hybrid cells constructed from the fusion of HEB7A, a HeLa tumor cell line carrying the mitochondrially coded chloramphenical (CAP) resistance mutation, and GM 2291, a limited lifespan human diploid fibroblast which is CAP sensitive. T
The inherited deficiency of galactosylceramide pgalactosidase (E.C. 3.2.1.46: galactocerebrosidase) activity results in globoid cell leukodystrophy in humans (Krabbe disease) and in mice (twitcher mutant). To determine whether Krabbe patients' cells complement twitcher cells to produce, in hybrid co