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GENETIC CONTROL OF LEISHMANIA MAJOR INFECTION IN CONGENIC, RECOMBINANT INBRED AND F2 POPULATIONS OF MICE

✍ Scribed by Mock, B. ;Blackwell, J. ;Hilgers, J. ;Potter, M. ;Nacy, C.

Book ID
114831104
Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
619 KB
Volume
20
Category
Article
ISSN
0960-7420

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Leishmania major infection of inbred mice leads to a major dichotomous responsedeath or survival-that depends on the strain of mice. This finding has motivated efforts to locate genetic determinants of disease susceptibility. Genotyping studies have confirmed a complex multilocus trait, but studies