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Genetic co-inactivation of macrophage- and T-tropic HIV-1 chemokine coreceptors CCR-5 and CXCR-4 by intrakines

✍ Scribed by Bai, X; Chen, J-D; Yang, A-G; Torti, F; Chen, S-Y


Book ID
110038223
Publisher
Nature Publishing Group
Year
1998
Tongue
English
Weight
285 KB
Volume
5
Category
Article
ISSN
0969-7128

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## Abstract Within the brain, HIV‐1 targets the microglia and astrocytes. Previous studies have reported that viral entry into astrocytes is independent of CD4, in contrast to microglia. We aimed to determine whether chemokine receptors play a role in mediating CD4‐independent HIV‐1 entry into astr