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Genetic characterization of methotrexate-resistant chinese hamster ovary cells

โœ Scribed by Wayne F. Flintoff; Susan M. Spindler; Louis Siminovitch

Book ID
112906010
Publisher
Society for In Vitro Biology
Year
1976
Tongue
English
Weight
678 KB
Volume
12
Category
Article
ISSN
1475-2689

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## Abstract Stable clones selected for resistance to tunicamycin (TM) have been isolated from Chinese Hamster Ovary (CHO) cells. The TM^R^ phenotype is stable for more than nine months in the absence of the drug. The morphology of TM^R^ mutant varies from epitheloid to abnormally elongate. The muta