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Genetic Causes of Female Infertility: Targeted Mutagenesis in Mice

✍ Scribed by Stephen Greenhouse; Tracy Rankin; Jurrien Dean


Book ID
117852441
Publisher
American Society of Human Genetics
Year
1998
Tongue
English
Weight
153 KB
Volume
62
Category
Article
ISSN
0002-9297

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Examples of the insertion of less than 10 bp of DNA sequence into human gene-coding regions causing genetic disease were collated in order to study the underlying causative mechanisms. The nature of these insertions was found to be consistent with several mechanisms of mutagenesis including: (1) sli