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Genetic association study of putative functional single nucleotide polymorphisms of genes in folate metabolism and spina bifida

โœ Scribed by Carla A. Martinez; Hope Northrup; Jone-Ing Lin; Alanna C. Morrison; Jack M. Fletcher; Gayle H. Tyerman; Kit Sing Au


Book ID
113435259
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
592 KB
Volume
201
Category
Article
ISSN
1097-6868

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## Background: Spina bifida is a class of neural tube defects, which are congenital malformations of the central nervous system with a prevalence of 0.5 to 12 per 1000 births globally. in this article we attempt to identify genes related to folate and its metabolic pathways that are involved in the