575: Results of a genetic association study of genes in folate metabolism and spina bifida
โ Scribed by Carla A. Martinez; Hope Northrup; Jone-Ing Lin; Alanna Morrison; Jack M. Fletcher; Gayle Tyerman; Kit Sing Au
- Book ID
- 113434600
- Publisher
- Elsevier Science
- Year
- 2008
- Tongue
- English
- Weight
- 242 KB
- Volume
- 199
- Category
- Article
- ISSN
- 1097-6868
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๐ SIMILAR VOLUMES
Defects of neural tube closure are among the most common of all human malformations. Epidemiological and genetic studies indicate that most of these defects are multifactorial in origin with genetic and environmental causes. Although periconceptional supplementation of the maternal diet with folic a
## Background: Spina bifida is a class of neural tube defects, which are congenital malformations of the central nervous system with a prevalence of 0.5 to 12 per 1000 births globally. in this article we attempt to identify genes related to folate and its metabolic pathways that are involved in the
Neural tube defects remain the most serious common birth defect and, despite considerable progress in understanding these malformations, the etiology of most cases remains unknown. It has been proposed that the cause may vary with the type and location of the malformation but, if these variables are