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Genetic association of the very low density lipoprotein (VLDL) receptor gene with sporadic Alzheimer's disease

✍ Scribed by Okuizumi, Kaoru; Onodera, Osamu; Namba, Yoshio; Ikeda, Kazuhiko; Yamamoto, Tokuo; Seki, Koji; Ueki, Akira; Nanko, Shinichiro; Tanaka, Hajime; Takahashi, Hitoshi


Book ID
109918276
Publisher
Nature Publishing Group
Year
1995
Tongue
English
Weight
359 KB
Volume
11
Category
Article
ISSN
1061-4036

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## Abstract A number of studies suggest that brain cholesterol metabolism may play a role in Alzheimer's disease (AD) development, probably through modulation of amyloid beta production. The discovery that apolipoprotein E (__APOE__) Ξ΅4 allele is a risk factor for sporadic AD raises the possibility