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Genetic Association of the R620W Polymorphism of Protein Tyrosine Phosphatase PTPN22 with Human SLE

✍ Scribed by Chieko Kyogoku; Ward A. Ortmann; Annette Lee; Scott Selby; Victoria E.H. Carlton; Monica Chang; Paula Ramos; Emily C. Baechler; Franak M. Batliwalla; Jill Novitzke; Adrienne H. Williams; Clarence Gillett; Peter Rodine; Robert R. Graham; Kristin G. Ardlie; Patrick M. Gaffney; Kathy L. Moser; Michelle Petri; Ann B. Begovich; Peter K. Gregersen; Carl D. Langefeld; Timothy W. Behrens

Book ID
117854495
Publisher
American Society of Human Genetics
Year
2004
Tongue
English
Weight
75 KB
Volume
75
Category
Article
ISSN
0002-9297

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## Abstract ## Objective The R620W (1858C→T) polymorphism in __PTPN2__2 has been implicated in type 1 diabetes mellitus, rheumatoid arthritis, Graves' disease, Hashimoto thyroiditis, autoimmune thyroid disease, and systemic lupus erythematosus (SLE). The aim of this study was to evaluate this poly