Tryptophan hydroxylase (TPH) is the rate-limiting enzyme in the synthesis of 5-hydroxytryptamine (5-HT). An association study in bipolar affective disorder I or unipolar major affective disorder was performed by using a Bfa I restriction site polymorphism within intron 7 of the tryptophan hydroxylas
Genetic association and sequencing of the insulin-like growth factor 1 gene in bipolar affective disorder
β Scribed by Ana C. Parente Pereira; Andrew McQuillin; Vinay Puri; Adebayo Anjorin; Nicholas Bass; Radhika Kandaswamy; Jacob Lawrence; David Curtis; Pamela Sklar; Shaun M. Purcell; Hugh M.D. Gurling
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 329 KB
- Volume
- 156
- Category
- Article
- ISSN
- 1552-4841
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
In the present study we sought to identify genetic variation in the adenosine A1 receptor (A1AR) gene on chromosome 1q31-32.1, which through alteration of protein function or level of expression might contribute to the genetic predisposition to bipolar affective disorder. We performed a systematic m
Monoamine oxidases catalyse the oxidative degradation of biogenic amines including neurotransmitters such as noradrenaline, dopamine, and 5-hydroxytryptamine (5-HT). Three groups have reported positive associations of the monoamine oxidase A (MAOA) gene with bipolar affective disorder although other
Insulin-like growth factor II (IGF-II) plays significant roles in the growth and development of mammals through the regulation of mitogenesis and cell survival. Previously, IGF-II mRNA transcripts within the CNS were detected in the choroid plexus and leptomeninges (DeChiara et al., 1991). The objec