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Genetic aspects of quantitative variation in the carbonic anhydrases of the pig-tailed macaque,Macaca nemestrina. I. Response to thyroxine

✍ Scribed by Stephen I. O. Anyaibe; Verle E. Headings

Publisher: Springer
Year: 1975
Tongue: English
Weight: 681 KB
Volume: 13
Category: Article
ISSN: 0006-2928
DOI: 10.1007/bf00484925

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✦ Synopsis

Effects of thyroxine on incorporation of L-serine-C 14 into four carbonic anhydrase isozymes (CA II, CA Ia, CA Ib, CA Ic) and hemoglobin were quantified in retieulocytes ofMacaca nemestrina in vitro. Response to thyroxine differed significantly between CA Ia and two allelic variants (CA Ib and CA Ic) and the nonallelic isozyme (CA H). The effects of thyroxine on serine incorporation into hemoglobin and three of the carbonic anhydrase isozymes were shown to be nonlinear with thyroxine concentration.

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