## Abstract Our objective was to report the clinical characteristics and to investigate the role of __SLITRK1__ gene in a large Italian family with Tourette syndrome (TS). The diagnosis of TS and chronic motor tics (CMT) was made according to βThe Tourette Syndrome Classification Study Groupβ (1993
Genetic and clinical analysis of a large Dutch Gilles de la Tourette family
β Scribed by Verkerk, A J M H; Cath, D C; van der Linde, H C; Both, J; Heutink, P; Breedveld, G; Aulchenko, Y S; Oostra, B A
- Book ID
- 110060155
- Publisher
- Nature Publishing Group
- Year
- 2006
- Tongue
- English
- Weight
- 999 KB
- Volume
- 11
- Category
- Article
- ISSN
- 1359-4184
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Although family and twin studies suggest that genetic factors are involved in the etiology of Tourette syndrome and other related tic disorders, further evidence is needed to demonstrate that the familial transmission is consistent with known genetic factors. We performed a complex segregation analy
## Abstract We describe a large family with a primary focal dystonia from a small Dutch village on a former island. Twentyβfour individuals spanning three generations were examined by two movementβdisorder neurologists. Two other movementβdisorder neurologists evaluated the videos independently. Su
Gfles de la Tourette Syndrome (TS) is a familial, neuropsychiatric disorder characterized by chronic, intermittent motor and vocal tics that typically appear in childhood although the clinical expression varies. Affected individuals may display additional symptoms, but the