We analyzed disease-marker associations in Problem 3 for the Genetic Analysis Workshop 11, using PAP for segregation analysis and LIPED for linkage analysis. In this report we present aspects of our analyses that are not reported in the summary [MacCluer et al, 19841. Certain features that we added
Genetic analysis workshop II: Results of segregation analyses using POINTER and linkage analyses using LIPED
โ Scribed by Nancy J. Cox
- Publisher
- John Wiley and Sons
- Year
- 1984
- Tongue
- English
- Weight
- 225 KB
- Volume
- 1
- Category
- Article
- ISSN
- 0741-0395
No coin nor oath required. For personal study only.
โฆ Synopsis
Genetic Analysis Workshop I1 Problems 2 and 3 were analyzed using the segregation analysis program POINTER and the linkage analysis program LIPED. Results of the segregation analyses were acceptable with respect to both parameter estimation and hypothesis testing. Results of the linkage analyses were also good. Although it was noted that the linkage and population association data were sometimes compatible with more than one hypothesis, the correct relationships among the trait and marker loci were generally among those found compatible with the data.
๐ SIMILAR VOLUMES
Data from the Framingham Heart Study were provided for Genetic Analysis Workshop 13. This paper summarizes six contributed papers that focused on the analysis of the longitudinal alcohol and/or cigarette use phenotypes available in these data, with the goal of detecting genes influencing these trait